1) about installation of net 4.6 is an update for 4.5, so both are connected ... in WinReducer if you remove 4.5 you will not be able to install 4.6
2) In WinReducer EX-81, you are able to automatically integrate net 4.6 using WinReducer :
- Go to "Updates Downloader" tool, select all entries in the category "Net Framework 4.6" and download them
- Once your edition mounted, go to the tab "System" and select "Integrate -> Integrate Updates" button, to choose the updates downloaded folder (you have nothing to do except hit "ok" botton)
- "APPLY" your changes, then Net Framework 4.5 will be automatically updated to v4.6 during the process
Two last things, you could remove Net Framework 3.5 without breaking 4.5 (or 4.6) ! And even if you remove 4.5, all WinReducer Software will always be compatible !
Have a nice day !